BDBM335713 4'-((1,1-Dioxidothiomorpholino) methyl)-5-(ethyl(tetrahydro-2H- pyran-4-yl)amino)-4-methyl-N- ((1-methyl-3-oxo-2,3,5,6,7,8- hexahydroisoquinolin-4- yl)methyl)-[1,1'-biphenyl]-3- carboxamide::US9738630, Example 8

SMILES CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c3CCCCc3c(C)[nH]c2=O)c1C)-c1ccc(CN2CCS(=O)(=O)CC2)cc1

InChI Key InChIKey=ZSPZMTFCVGTTDR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335713   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335713(US9738630, Example 8 | 4'-((1,1-Dioxidothiomorphol...)
Affinity DataEC50: <500nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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