BDBM335703 (R)-3-(6-(5-fluoroquinolin-7-yl)-2-hydroxypyridin-3-yl)-3-methylpiperidin-2-one::US9738626, 6 (TFA salt)

SMILES C[C@@]1(CCCNC1=O)c1ccc(nc1O)-c1cc(F)c2cccnc2c1

InChI Key InChIKey=QEUAUMWHNLVMDZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335703   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

US Patent
LigandPNGBDBM335703(US9738626, 6 (TFA salt) | (R)-3-(6-(5-fluoroquinol...)
Affinity DataKi:  48.6nMAssay Description:To measure the ability of test compounds in the present invention to bind to the human EP3 receptor, and therefore have the potential to antagonize P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent