BDBM335632 5-((4-aminopiperidin-1-yl)methyl)-N-(5-(2-isopropyl-2H-tetrazol-5-yl)-1H-indol-7-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine::US9737542, Example 74

SMILES CC(C)(C)OC(=O)NC1CCN(Cc2cc(Br)n3ncnc(Nc4cc(cc5cc[nH]c45)C#N)c23)CC1

InChI Key InChIKey=MQGPCAMZYUZZSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335632   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335632(US9737542, Example 74 | 5-((4-aminopiperidin-1-yl)...)
Affinity DataIC50: 55nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent