BDBM335488 US11548901, Compound 40::US9732092, Compound 40

SMILES CC1C[C@H]2C[C@@H]1O[C@@H]1Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N21

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335488   

TargetSolute carrier family 22 member 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM335488(US9732092, Compound 40 | US11548901, Compound 40)
Affinity DataIC50: 204nMAssay Description:Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
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TargetSolute carrier family 22 member 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM335488(US9732092, Compound 40 | US11548901, Compound 40)
Affinity DataIC50: 204nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
Go to US Patent