BDBM3353 2,2 -Diselenobis[1-methyl-1H-indole-3-carboxylic acid]::2-[(3-carboxy-1-methyl-1H-indol-2-yl)diselanyl]-1-methyl-1H-indole-3-carboxylic acid::diselenobis(1H-indole) deriv. 22

SMILES Cn1c([Se][Se]c2c(C(O)=O)c3ccccc3n2C)c(C(O)=O)c2ccccc12

InChI Key InChIKey=HNEORRPIDMAPCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3353   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3353(2-[(3-carboxy-1-methyl-1H-indol-2-yl)diselanyl]-1-...)
Affinity DataIC50: 3.50E+3nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3353(2-[(3-carboxy-1-methyl-1H-indol-2-yl)diselanyl]-1-...)
Affinity DataIC50: 1.74E+4nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3353(2-[(3-carboxy-1-methyl-1H-indol-2-yl)diselanyl]-1-...)
Affinity DataIC50: 2.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2005
Entry Details Article
PubMed