BDBM334769 US11040966, Example 4.127::US9732075, Example 4.127::[(2S,3S)-2-(4-Chloro-1H-benzoimidazol-2-yl)-3-methyl-pyrrolidin-1-yl]-[2-(3,4-dimethyl-phenyl)-thiophen-3-yl]-methanone

SMILES C[C@H]1CCN([C@@H]1c1nc2c(Cl)cccc2[nH]1)C(=O)c1ccsc1-c1ccc(C)c(C)c1

InChI Key InChIKey=PYSPVSXASXGIRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 334769   

TargetOrexin/Hypocretin receptor type 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334769(US9732075, Example 4.127 | [(2S,3S)-2-(4-Chloro-1H...)
Affinity DataIC50: 1nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
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TargetOrexin receptor type 2(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334769(US9732075, Example 4.127 | [(2S,3S)-2-(4-Chloro-1H...)
Affinity DataIC50: 19nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent