BDBM334640 US11040966, Example 3.9::US9732075, Example 3.9::[(2S,4R)-2-(5-Chloro-4-methyl-1H-benzoimidazol-2-yl)-4-methoxy-pyrrolidin-1-yl]-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone

SMILES CO[C@@H]1C[C@H](N(C1)C(=O)c1nc(C)sc1-c1cccc(Cl)c1)c1nc2c(C)c(Cl)ccc2[nH]1

InChI Key InChIKey=ORXQOPADZCARMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 334640   

TargetOrexin/Hypocretin receptor type 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334640(US9732075, Example 3.9 | [(2S,4R)-2-(5-Chloro-4-me...)
Affinity DataIC50: 1nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
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TargetOrexin receptor type 2(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM334640(US9732075, Example 3.9 | [(2S,4R)-2-(5-Chloro-4-me...)
Affinity DataIC50: 2nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent