BDBM33418 pyrimidinol carboxylic acid, 10

SMILES COc1ccc(Cc2nc(C(O)=O)c(O)c(=O)[nH]2)cc1Br

InChI Key InChIKey=LQQYBZYFFRDXNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33418   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM33418(pyrimidinol carboxylic acid, 10)
Affinity DataIC50: 1.15E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2009
Entry Details Article
PubMed
TargetRibonuclease H1(Human)
Gilead Sciences

LigandPNGBDBM33418(pyrimidinol carboxylic acid, 10)
Affinity DataIC50: 7.40E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2009
Entry Details Article
PubMed