BDBM33417 pyrimidinol carboxylic acid, 9

SMILES OC(=O)c1nc(Cc2ccc(Cl)c(Cl)c2)[nH]c(=O)c1O

InChI Key InChIKey=OZDSTVKQUHMIRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33417   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM33417(pyrimidinol carboxylic acid, 9)
Affinity DataIC50: 1.45E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2009
Entry Details Article
PubMed
TargetRibonuclease H1(Human)
Gilead Sciences

LigandPNGBDBM33417(pyrimidinol carboxylic acid, 9)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2009
Entry Details Article
PubMed