BDBM33407 2,4-diaminofuro[2,3-d]pyrimidine, 13

SMILES CCC(C)C(Cc1coc2nc(N)nc(N)c12)c1ccccc1OC

InChI Key InChIKey=AYLKSELOGWVDPG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 33407   

TargetEpidermal growth factor receptor(Human)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 2.00E+5nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 1.74E+4nMpH: 7.4 T: 2°CAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 5.00E+5nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 1.54E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 4.21E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 3.45E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 4.45E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

LigandPNGBDBM33407(2,4-diaminofuro[2,3-d]pyrimidine, 13)
Affinity DataIC50: 4.51E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMed