BDBM333295 US10196396, Compound 90::methyl3-(((3-((2S,3R,4S)-3,4-dihydroxytetrahydrothiophen-2-yl)-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)amino)methyl)benzoate

SMILES COC(=O)c1cccc(CNc2nccn3c(nnc23)[C@@H]2SC[C@@H](O)[C@H]2O)c1

InChI Key InChIKey=IZEVZEPPKKYGEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333295   

TargetAdenosine receptor A3(Human)
Handok

US Patent
LigandPNGBDBM333295(US10196396, Compound 90 | methyl3-(((3-((2S,3R,4S)...)
Affinity DataIC50: 55nMAssay Description:HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
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