BDBM333239 3-chloro-N-(3-((2S,3R,4S)-3,4-dihydroxytetrahydrothiophen-2-yl)-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)benzenesulfonamide::US10196396, Compound 34

SMILES O[C@@H]1CS[C@H]([C@@H]1O)c1nnc2c(NS(=O)(=O)c3cccc(Cl)c3)nccn12

InChI Key InChIKey=HKPQBDKXBXPJBW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 333239   

TargetAdenosine receptor A3(Human)
Handok

US Patent
LigandPNGBDBM333239(US10196396, Compound 34 | 3-chloro-N-(3-((2S,3R,4S...)
Affinity DataIC50: 55nMAssay Description:HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
Go to US Patent

TargetAdenosine receptor A3(Human)
Handok

US Patent
LigandPNGBDBM333239(US10196396, Compound 34 | 3-chloro-N-(3-((2S,3R,4S...)
Affinity DataKi:  55nMAssay Description:HEK-293 cell membrane homogenates (32 μg protein), in which A3 adenosine receptors were expressed, are incubated for 120 min at 22° C. with 0.15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
Go to US Patent