BDBM333115 6-(4-chloro-6-methoxy-2-pyridyl)-2-pyrimidin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine::US10196391, Example 115

SMILES COc1cc(Cl)cc(n1)N1CCc2nc(ncc2C1)-c1ncccn1

InChI Key InChIKey=UIKZFMGNSLRGAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333115   

TargetGenome polyprotein(Hepatitis GB virus B)
Hoffmann-La Roche

US Patent
LigandPNGBDBM333115(US10196391, Example 115 | 6-(4-chloro-6-methoxy-2-...)
Affinity DataIC50: 352nMAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2019
Entry Details
Go to US Patent