BDBM33269 CHEMBL277836::azo-sulfonamide, 1d::cid_75522::p-Phenyldiazenyl derivative, 4

SMILES CN(C)c1ccc(cc1)\N=N\c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=NZUPTIDAKYYKGC-UHFFFAOYSA-N

Data  9 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 33269   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetProstaglandin G/H synthase 1(Human)
National Research Institute of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 assessed as TBX2 production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  6.60nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  7.90nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  30nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  621nM ΔG°:  -8.46kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  638nM ΔG°:  -8.45kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  638nM ΔG°:  -8.45kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  638nMAssay Description:Inhibition of human cloned full length carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  6.86E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM33269(CHEMBL277836 | p-Phenyldiazenyl derivative, 4 | ci...)
Affinity DataKi:  3.07E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed