BDBM332402 US10196353, Example 17::US11299457, Example 17

SMILES CSCC(C)n1c(cc2c(C#N)c(ccc12)C#N)C(F)F

InChI Key InChIKey=USUVLGWDWVYTDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332402   

TargetProgesterone receptor(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM332402(US10196353, Example 17 | US11299457, Example 17)
Affinity DataIC50: 79.4nMAssay Description:Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
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TargetAndrogen receptor(Human)
Glaxosmithkline Intellectual Property (No. 2)

US Patent
LigandPNGBDBM332402(US10196353, Example 17 | US11299457, Example 17)
Affinity DataIC50: 79.4nMAssay Description:The androgen receptor fluorescence polarization assay is used to investigate the interaction of the compounds with the androgen receptor.Compounds ar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
Go to US Patent