BDBM33201 2-methyl-5,8-bis(oxidanyl)naphthalene-1,4-dione::5,8-dihydroxy-2-methyl-1,4-naphthoquinone::5,8-dihydroxy-2-methylnaphthalene-1,4-dione::MLS001048870::SMR000387073::cid_271296

SMILES CC1=CC(=O)c2c(O)ccc(O)c2C1=O

InChI Key InChIKey=YKPXIWHBRBFRQM-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 33201   

TargetBcl-2-related protein A1(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataEC50:  2.87E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataEC50:  2.14E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataIC50: 1.03E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetCore protein(Hepacivirus C)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataIC50: 4.98E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetProtein Rev(Human immunodeficiency virus type 1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataIC50: 7.54E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetFemale germline-specific tumor suppressor gld-1(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataIC50: 5.58E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetThioredoxin reductase 1, cytoplasmic(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataIC50: 700nMAssay Description:Inhibition of NADPH-reduced rat TrxR1 assessed as suppression of DTNB reduction incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM33201(MLS001048870 | cid_271296 | 2-methyl-5,8-bis(oxida...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of TrxR1 in human HL60 cells incubated for 24 hrs by endpoint insulin reduction assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2020
Entry Details Article
PubMed