BDBM331650 Preparation of 5-(4-(2-((5-(tert-butyl)isoxazol-3-yl)amino)-2-oxoethyl)phenyl)-N-(2-(methylsulfonyl)ethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide::US9725465, Example 68

SMILES CC(C)(C)c1cc(NC(=O)Cc2ccc(cc2)-c2cnc3[nH]c(cc3c2)C(=O)NCCS(C)(=O)=O)no1

InChI Key InChIKey=SLMWBFVNASSHIM-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331650   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ambit Biosciences

US Patent
LigandPNGBDBM331650(US9725465, Example 68 | Preparation of 5-(4-(2-((5...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetMast/stem cell growth factor receptor Kit(Human)
Ambit Biosciences

US Patent
LigandPNGBDBM331650(US9725465, Example 68 | Preparation of 5-(4-(2-((5...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent