BDBM331644 Preparation of N-(5-(tert-butyl)isoxazol-3-yl)-2-(2-fluoro-4-(3-(1-hydroxyethyl)-1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl)acetamide::US9725465, Example 62

SMILES CC(O)c1n[nH]c2ncc(cc12)-c1ccc(CC(=O)Nc2cc(on2)C(C)(C)C)c(F)c1

InChI Key InChIKey=GVQUEHAPCSDWKL-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331644   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ambit Biosciences

US Patent
LigandPNGBDBM331644(US9725465, Example 62 | Preparation of N-(5-(tert-...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetMast/stem cell growth factor receptor Kit(Human)
Ambit Biosciences

US Patent
LigandPNGBDBM331644(US9725465, Example 62 | Preparation of N-(5-(tert-...)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent