BDBM33157 MLS000687602::SMR000283375::[2,3-bis(2-furanyl)-6-quinoxalinyl]-phenylmethanone::[2,3-bis(2-furyl)quinoxalin-6-yl]-phenyl-methanone::[2,3-bis(furan-2-yl)quinoxalin-6-yl]-phenyl-methanone::[2,3-bis(furan-2-yl)quinoxalin-6-yl]-phenylmethanone::cid_1037240

SMILES O=C(c1ccccc1)c1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1

InChI Key InChIKey=JMIHJEGISAXHQH-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 33157   

TargetBcl-2-related protein A1(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33157(cid_1037240 | [2,3-bis(2-furanyl)-6-quinoxalinyl]-...)
Affinity DataEC50:  9.94E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetBcl-2-like protein 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33157(cid_1037240 | [2,3-bis(2-furanyl)-6-quinoxalinyl]-...)
Affinity DataEC50:  1.48E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetApoptosis regulator Bcl-2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33157(cid_1037240 | [2,3-bis(2-furanyl)-6-quinoxalinyl]-...)
Affinity DataEC50:  1.60E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
LigandPNGBDBM33157(cid_1037240 | [2,3-bis(2-furanyl)-6-quinoxalinyl]-...)
Affinity DataEC50:  4.55E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
LigandPNGBDBM33157(cid_1037240 | [2,3-bis(2-furanyl)-6-quinoxalinyl]-...)
Affinity DataIC50: 6.46E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM33157(cid_1037240 | [2,3-bis(2-furanyl)-6-quinoxalinyl]-...)
Affinity DataEC50:  3.23E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay