BDBM33124 2-Chloro-3-[4-(2-nitro-phenyl)-piperazin-1-yl]-[1,4]naphthoquinone::2-chloranyl-3-[4-(2-nitrophenyl)piperazin-1-yl]naphthalene-1,4-dione::2-chloro-3-[4-(2-nitrophenyl)-1-piperazinyl]naphthalene-1,4-dione::2-chloro-3-[4-(2-nitrophenyl)piperazin-1-yl]naphthalene-1,4-dione::2-chloro-3-[4-(2-nitrophenyl)piperazino]-1,4-naphthoquinone::MLS000588199::SMR000220218::cid_4561725

SMILES [O-][N+](=O)c1ccccc1N1CCN(CC1)C1=C(Cl)C(=O)c2ccccc2C1=O

InChI Key InChIKey=SPHZCDKPHYBGQR-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 33124   

TargetBcl-2-related protein A1(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33124(cid_4561725 | 2-chloro-3-[4-(2-nitrophenyl)piperaz...)
Affinity DataEC50:  360nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetBcl-2-related protein A1(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33124(cid_4561725 | 2-chloro-3-[4-(2-nitrophenyl)piperaz...)
Affinity DataEC50:  2.68E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein phosphatase PP1-alpha catalytic subunit(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33124(cid_4561725 | 2-chloro-3-[4-(2-nitrophenyl)piperaz...)
Affinity DataIC50: 6.70E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein phosphatase(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33124(cid_4561725 | 2-chloro-3-[4-(2-nitrophenyl)piperaz...)
Affinity DataIC50: 2.95E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM33124(cid_4561725 | 2-chloro-3-[4-(2-nitrophenyl)piperaz...)
Affinity DataEC50:  734nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetBeta-galactosidase(Escherichia coli)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33124(cid_4561725 | 2-chloro-3-[4-(2-nitrophenyl)piperaz...)
Affinity DataIC50: 6.66E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetC-C chemokine receptor type 6(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33124(cid_4561725 | 2-chloro-3-[4-(2-nitrophenyl)piperaz...)
Affinity DataIC50: 2.93E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay