BDBM331214 5-(Dimethyl-1,2-oxazol-4-yl)-8-[(S)-(2-fluorophenyl)(oxan-4-yl)methyl]-10-methanesulfonyl-13-methoxy-3,8,12-triazatricyclo[7.4.0.02,7]trideca-1(13),2::US9725449, Example 48

SMILES COc1ncc(c2n([C@@H](C3CCOCC3)c3ccccc3F)c3cc(cnc3c12)-c1c(C)noc1C)S(C)(=O)=O

InChI Key InChIKey=DNPSJOXDIBTLHM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 331214   

TargetBromodomain-containing protein 4 [1-477]/[333-460]/[44-168]/[44-460](Human)
Bristol-Myers Squibb

US Patent

LigandBDBM331214(5-(Dimethyl-1,2-oxazol-4-yl)-8-[(S)-(2-fluoropheny...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2019
Entry Details
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