BDBM33095 6-Methoxy-1,3-dimethyl-1H-benzo[de]cinnoline::MLS000554700::SMR000146817::cid_611216

SMILES COc1ccc2c(C)nn(C)c3cccc1c23

InChI Key InChIKey=DXWZBFBWUGZCLO-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 33095   

TargetBcl-2-related protein A1(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33095(MLS000554700 | SMR000146817 | 6-Methoxy-1,3-dimeth...)
Affinity DataEC50:  610nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetBcl-2-like protein 2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33095(MLS000554700 | SMR000146817 | 6-Methoxy-1,3-dimeth...)
Affinity DataEC50:  1.56E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetApoptosis regulator Bcl-2(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33095(MLS000554700 | SMR000146817 | 6-Methoxy-1,3-dimeth...)
Affinity DataEC50:  2.01E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
LigandPNGBDBM33095(MLS000554700 | SMR000146817 | 6-Methoxy-1,3-dimeth...)
Affinity DataIC50: 1.33E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetProtein artemis(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33095(MLS000554700 | SMR000146817 | 6-Methoxy-1,3-dimeth...)
Affinity DataIC50: 2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay