BDBM330444 US9725433, 100::methyl 4-{N-[(5-{4-[4-({[(2- fluoro-5-methylphenyl)amino] carbonyl}amino)phenoxy] pyridin-2-yl}-1H-pyrrol-3- yl)carbonyl]-S- methylsulfonimidoyl} butanoate

SMILES COC(=O)CCCS(C)(=O)=NC(=O)c1c[nH]c(c1)-c1cc(Oc2ccc(NC(=O)Nc3cc(C)ccc3F)cc2)ccn1

InChI Key InChIKey=KXYRKHSLATWDEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330444   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM330444(methyl 4-{N-[(5-{4-[4-({[(2- fluoro-5-methylphenyl...)
Affinity DataIC50: 13nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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