BDBM330359 N-ethyl-5-(4-{3-[(3- methyl-2- furoyl)amino]phenoxy} pyridin-2-yl)-1H-pyrrole-3- carboxamide::US9725433, 14

SMILES CCNC(=O)c1c[nH]c(c1)-c1cc(Oc2cccc(NC(=O)c3occc3C)c2)ccn1

InChI Key InChIKey=DBWLZXDWSDEPMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330359   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM330359(N-ethyl-5-(4-{3-[(3- methyl-2- furoyl)amino]phenox...)
Affinity DataIC50: 33nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetVascular endothelial growth factor receptor 1(Human)
Allergan

US Patent
LigandPNGBDBM330359(N-ethyl-5-(4-{3-[(3- methyl-2- furoyl)amino]phenox...)
Affinity DataIC50: 15nMAssay Description:The cytoplasmic domain of the human VEGF receptor (VEGFR-2) was expressed as a Histidine-tagged fusion protein following infection of insect cells us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent