BDBM3303 4-Anilinoquinazoline deriv. 54::4-N-(3-bromophenyl)quinazoline-4,6,7-triamine::4[ (3-Bromophenyl)aminol-6,7-diaminoquinazoline::CHEMBL328216

SMILES Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N

InChI Key InChIKey=ADXSZLCTQCWMTE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 3303   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-N-(3-bromophenyl)quinazoline-4,6,7-triamine | CH...)
Affinity DataIC50: 0.120nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-N-(3-bromophenyl)quinazoline-4,6,7-triamine | CH...)
Affinity DataIC50: 0.120nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-N-(3-bromophenyl)quinazoline-4,6,7-triamine | CH...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-N-(3-bromophenyl)quinazoline-4,6,7-triamine | CH...)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-N-(3-bromophenyl)quinazoline-4,6,7-triamine | CH...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-N-(3-bromophenyl)quinazoline-4,6,7-triamine | CH...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of wild type EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed