BDBM330223 (RS)-1-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-yl)phenyl]-3-[4-(trifluoromethyl)phenyl]urea::US9663530, Example 67

SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)C23CCC(CO2)NC3)cc1

InChI Key InChIKey=DZIMZTRBPKPCRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330223   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330223(US9663530, Example 67 | (RS)-1-[4-(5-Oxa-2-azabicy...)
Affinity DataIC50: 13.7nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330223(US9663530, Example 67 | (RS)-1-[4-(5-Oxa-2-azabicy...)
Affinity DataIC50: 26.3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent