BDBM330212 N-[4-[(1R,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]phenyl]-2-(trifluoromethyl)pyrimidin-4-amine::US9663530, Example 56

SMILES FC(F)(F)c1nccc(Nc2ccc(cc2)[C@@]23CN[C@@H](CO2)C3)n1

InChI Key InChIKey=BYCRBNADMVBJPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330212   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330212(US9663530, Example 56 | N-[4-[(1R,4S)-5-Oxa-2-azab...)
Affinity DataIC50: 39.3nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330212(US9663530, Example 56 | N-[4-[(1R,4S)-5-Oxa-2-azab...)
Affinity DataIC50: 2.41E+3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent