BDBM330193 (RS)—N-[4-(5-Oxa-2-azabicyclo[2.2.2]octan-4-yl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide::US9663530, Example 37

SMILES FC(F)(F)c1cc(ccn1)C(=O)Nc1ccc(cc1)C12CCC(CO1)NC2

InChI Key InChIKey=FONYOZSKQITKLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330193   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330193(US9663530, Example 37 | (RS)—N-[4-(5-Oxa-2-az...)
Affinity DataIC50: 37.7nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330193(US9663530, Example 37 | (RS)—N-[4-(5-Oxa-2-az...)
Affinity DataIC50: 1.44E+3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent