BDBM330168 (RS)-6-Ethoxy-N-[4-(5-oxa-2-azabicyclo[2.2.2]octan-4-yl)phenyl]pyridine-3-carboxamide::US9663530, Example 12

SMILES CCOc1ccc(cn1)C(=O)Nc1ccc(cc1)C12CCC(CO1)NC2

InChI Key InChIKey=JLAWDFPIRQCKLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330168   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330168(US9663530, Example 12 | (RS)-6-Ethoxy-N-[4-(5-oxa-...)
Affinity DataIC50: 21.9nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330168(US9663530, Example 12 | (RS)-6-Ethoxy-N-[4-(5-oxa-...)
Affinity DataIC50: 7.06E+3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent