BDBM330166 1-[4-[[(1S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]methyl]phenyl]-3-[3-(trifluoromethyl)phenyl]urea::US9663530, Example 10

SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(C[C@]34CN[C@H](CO3)C4)cc2)c1

InChI Key InChIKey=SOIFOPJZEGZLML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330166   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330166(US9663530, Example 10 | 1-[4-[[(1S,4S)-5-Oxa-2-aza...)
Affinity DataIC50: 364nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330166(US9663530, Example 10 | 1-[4-[[(1S,4S)-5-Oxa-2-aza...)
Affinity DataIC50: 20.9nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent