BDBM330164 1-[4-[[(1S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]methyl]phenyl]-3-[4-(trifluoromethyl)phenyl]urea::US9663530, Example 8

SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(C[C@]34CN[C@H](CO3)C4)cc2)cc1

InChI Key InChIKey=ZBSZXJJOXLZGBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330164   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330164(US9663530, Example 8 | 1-[4-[[(1S,4S)-5-Oxa-2-azab...)
Affinity DataIC50: 846nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330164(US9663530, Example 8 | 1-[4-[[(1S,4S)-5-Oxa-2-azab...)
Affinity DataIC50: 44.2nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent