BDBM330159 (RS)-5-Chloro-N-[4-(5-oxa-2-azabicyclo[2.2.2]octan-4-yl)phenyl]pyridin-2-amine::US9663530, Example 3

SMILES Clc1ccc(Nc2ccc(cc2)C23CCC(CO2)NC3)nc1

InChI Key InChIKey=MINPZJOKKYBPMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330159   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330159(US9663530, Example 3 | (RS)-5-Chloro-N-[4-(5-oxa-2...)
Affinity DataIC50: 14.1nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM330159(US9663530, Example 3 | (RS)-5-Chloro-N-[4-(5-oxa-2...)
Affinity DataIC50: 2.46E+3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent