BDBM330133 N-(5H-chromeno[3,4- c]pyridin-8-yl)-2,3- dihydro-1H-indene-2- carboxamide::US9663529, Example I-72

SMILES O=C(Nc1ccc-2c(OCc3cnccc-23)c1)C1Cc2ccccc2C1

InChI Key InChIKey=UOJNRGBOIIEOIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330133   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330133(US9663529, Example I-72 | N-(5H-chromeno[3,4- c]py...)
Affinity DataIC50: 58.7nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent