BDBM330073 N-(5H-chromeno[3,4- c]pyridin-8-yl)-2-m- tolylacetamide::US9663529, Example I-12

SMILES Cc1cccc(CC(=O)Nc2ccc-3c(OCc4cnccc-34)c2)c1

InChI Key InChIKey=IQEQLXWOYIJADX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330073   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330073(US9663529, Example I-12 | N-(5H-chromeno[3,4- c]py...)
Affinity DataIC50: 74.5nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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