BDBM329787 Preparation of 2-[(4R)-6-(4-chlorophenyl)-1-methyl-8-(trifluoromethoxy)-4H-[1,2,4]triazolo[4,3-a][1]benzazepin-4-yl]-N-ethylacetamide::US9663523, Example 52

SMILES CCNC(=O)C[C@@H]1C=C(c2ccc(Cl)cc2)c2cc(OC(F)(F)F)ccc2-n2c(C)nnc12

InChI Key InChIKey=VRSAVAUXYKCRST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329787   

TargetBromodomain-containing protein 4(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM329787(US9663523, Example 52 | Preparation of 2-[(4R)-6-(...)
Affinity DataIC50: 190nMAssay Description:For this purpose, a time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used, which measures the binding between N-terminally Hi...More data for this Ligand-Target Pair
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Date in BDB:
6/4/2019
Entry Details
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