BDBM329784 Preparation of 6-(4-chlorophenyl)-8-(3,5-dimethyl-1,2-oxazol-4-yl)-1-methyl-4-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]-4H-[1,2,4]triazolo[4,3-a][1]benzazepine::US9663523, Example 48

SMILES Cc1nnc(CC2C=C(c3ccc(Cl)cc3)c3cc(ccc3-n3c(C)nnc23)-c2c(C)noc2C)o1

InChI Key InChIKey=VBNLIRSQBFUZDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329784   

TargetBromodomain-containing protein 4(Human)
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US Patent
LigandPNGBDBM329784(US9663523, Example 48 | Preparation of 6-(4-chloro...)
Affinity DataIC50: 340nMAssay Description:For this purpose, a time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used, which measures the binding between N-terminally Hi...More data for this Ligand-Target Pair
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Date in BDB:
6/4/2019
Entry Details
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