BDBM329735 (S)-1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)- 6-(3-methoxypyrrolidine- 1-carbonyl)-1H-indazol- 3-yl)piperidine-4- carboxylic acid::US9663522, 12C

SMILES CO[C@H]1CCN(C1)C(=O)c1ccc2c(nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2c1)N1CCC(CC1)C(O)=O

InChI Key InChIKey=OJPULHLDJJKGHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329735   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329735(US9663522, 12C | (S)-1-(1-(2-chloro-6- (trifluorom...)
Affinity DataIC50: 30nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent