BDBM329734 (S)-1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)- 6-(2-methylpyrrolidine-1- carbonyl)-1H-indazol-3- yl)piperidine-4-carboxylic acid::US9663522, 12B

SMILES C[C@H]1CCCN1C(=O)c1ccc2c(nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2c1)N1CCC(CC1)C(O)=O

InChI Key InChIKey=COCRJDBZMZXHBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329734   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329734(US9663522, 12B | (S)-1-(1-(2-chloro-6- (trifluorom...)
Affinity DataIC50: 139nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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