BDBM329716 1-(1-(2-chloro-6- cyclobutylbenzoyl)- 4-fluoro-1H- indazol-3- yl)piperidine-4- carboxylic acid::US9663522, 3B

SMILES OC(=O)C1CCN(CC1)c1nn(C(=O)c2c(Cl)cccc2C2CCC2)c2cccc(F)c12

InChI Key InChIKey=BNBKRQYNTMUXOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329716   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329716(US9663522, 3B | 1-(1-(2-chloro-6- cyclobutylbenzoy...)
Affinity DataIC50: 3nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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