BDBM329714 1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)-4-methyl- 1H-indazol-3- yl)piperidine-4- carboxylic acid::US9663522, 2B

SMILES Cc1cccc2n(nc(N3CCC(CC3)C(O)=O)c12)C(=O)c1c(Cl)cccc1C(F)(F)F

InChI Key InChIKey=DYKSGOSMHKUSKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329714   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329714(US9663522, 2B | 1-(1-(2-chloro-6- (trifluoromethyl...)
Affinity DataIC50: 20nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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