BDBM329710 2-(1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)-1H- pyrazolo[4,3- b]pyridin-3- yl)azetidin-3- yl)acetic acid::US9663522, 1Q

SMILES OC(=O)CC1CN(C1)c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cccnc12

InChI Key InChIKey=ZZCSAFFKHDIDKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329710   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329710(US9663522, 1Q | 2-(1-(1-(2-chloro-6- (trifluoromet...)
Affinity DataIC50: 7.44E+3nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
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Date in BDB:
6/4/2019
Entry Details
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