BDBM329654 US11001583, Compound 10::US9663515, Compound 10

SMILES CCS(=O)(=O)c1ccc(nc1)[C@H](COC(N)=O)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1

InChI Key InChIKey=JJFRLGYXYFVWBX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329654   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM329654(US9663515, Compound 10 | US11001583, Compound 10)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM329654(US9663515, Compound 10 | US11001583, Compound 10)
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent