BDBM329516 2-((1S,2S)-2-((2-methyl-5- (3-methylimidazo[1,2- a]pyridin-6-yl)pyrimidin-4- yloxy)methyl)cyclopropyl) quinoline::US9663513, 129

SMILES Cc1cnc2ccc(cn12)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc2ccccc2n1

InChI Key InChIKey=GWJHEKKLCZJDOK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329516   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329516(US9663513, 129 | 2-((1S,2S)-2-((2-methyl-5- (3-met...)
Affinity DataKi:  0.0200nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP FP kit supplied by Molecular Devices, Sunnyv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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