BDBM329476 1-(5-(4-(((1S,2S)-2-(5- methoxypyridin-2- yl)cyclopropyl)methoxy)- 2-methylpyrimidin-5- yl)pyridin-2- yl)cyclopentanol::US9663513, 89

SMILES COc1ccc(nc1)[C@H]1C[C@@H]1COc1nc(C)ncc1-c1ccc(nc1)C1(O)CCCC1

InChI Key InChIKey=DCCRGBWEADJTJW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329476   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329476(US9663513, 89 | 1-(5-(4-(((1S,2S)-2-(5- methoxypyr...)
Affinity DataKi:  0.0600nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP FP kit supplied by Molecular Devices, Sunnyv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
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