BDBM3291 4-Anilinoquinazoline deriv. 42::4-N-(3-bromophenyl)quinazoline-4,5-diamine

SMILES Nc1cccc2ncnc(Nc3cccc(Br)c3)c12

InChI Key InChIKey=VFDHVXMKHJATKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3291   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3291(4-N-(3-bromophenyl)quinazoline-4,5-diamine | 4-Ani...)
Affinity DataIC50: 439nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2005
Entry Details Article
PubMed