BDBM329 (3R,4S,5S,6R)-3,6-Bis(phenoxymethyl)-2,7-bis[4-(2-thienyl)benzyl]-4,5-dihydroxy-1,2,7-thiadiazepine 1,1-Dioxide::(3R,4S,5S,6R)-4,5-dihydroxy-3,6-bis(phenoxymethyl)-2,7-bis({[4-(thiophen-2-yl)phenyl]methyl})-1,2,7-thiadiazepane-1,1-dione::CHEMBL345997::Cyclic Sulfamide deriv. 7

SMILES O[C@@H]1[C@@H](O)[C@@H](COc2ccccc2)N(Cc2ccc(cc2)-c2cccs2)S(=O)(=O)N(Cc2ccc(cc2)-c2cccs2)[C@@H]1COc1ccccc1

InChI Key InChIKey=UMDCQGGNNGRKRN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM329((3R,4S,5S,6R)-4,5-dihydroxy-3,6-bis(phenoxymethyl)...)
Affinity DataKi:  920nM ΔG°:  -8.37kcal/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM329((3R,4S,5S,6R)-4,5-dihydroxy-3,6-bis(phenoxymethyl)...)
Affinity DataKi:  920nMAssay Description:Association rate constant for the interaction between inhibitor and HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed