BDBM328994 5-[[4-[[(2S)-morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile::US11787792, Compound 2::US9663503, Compound 2

SMILES FC(F)(F)c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@@H]1CNCCO1

InChI Key InChIKey=YBYYWUUUGCNAHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328994   

TargetSerine/threonine-protein kinase Chk1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM328994(US9663503, Compound 2 | 5-[[4-[[(2S)-morpholin-2-y...)
Affinity DataIC50: 2.10nMAssay Description:CHK1 kinase activity was measured in a microfluidic assay that monitors the separation of a phosphorylated product from its substrate. The assay was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase Chk1(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM328994(US9663503, Compound 2 | 5-[[4-[[(2S)-morpholin-2-y...)
Affinity DataIC50: 2.10nMAssay Description:CHK1 kinase activity was measured in a microfluidic assay that monitors the separation of a phosphorylated product from its substrate. The assay was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
Go to US Patent