BDBM32853 (1,3-dioxoisoindol-2-yl) 2,4-dimethylbenzenesulfonate::2,4-dimethylbenzenesulfonic acid (1,3-dioxo-2-isoindolyl) ester::2,4-dimethylbenzenesulfonic acid phthalimido ester::2-{[(2,4-dimethylphenyl)sulfonyl]oxy}-1H-isoindole-1,3(2H)-dione::MLS000579570::SMR000199007::[1,3-bis(oxidanylidene)isoindol-2-yl] 2,4-dimethylbenzenesulfonate::cid_2196572

SMILES Cc1ccc(c(C)c1)S(=O)(=O)ON1C(=O)c2ccccc2C1=O

InChI Key InChIKey=CFYUCVMWWSCWHI-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32853   

TargetProthrombin(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32853(MLS000579570 | 2-{[(2,4-dimethylphenyl)sulfonyl]ox...)
Affinity DataIC50: 856nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2009
Entry Details
PCBioAssay
TargetCoagulation factor XI(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32853(MLS000579570 | 2-{[(2,4-dimethylphenyl)sulfonyl]ox...)
Affinity DataIC50: 1.08E+3nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2009
Entry Details
PCBioAssay
TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32853(MLS000579570 | 2-{[(2,4-dimethylphenyl)sulfonyl]ox...)
Affinity DataIC50: 8.48E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
Target60S ribosomal protein L19-A(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32853(MLS000579570 | 2-{[(2,4-dimethylphenyl)sulfonyl]ox...)
Affinity DataEC50:  1.40E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetVacuolar aminopeptidase 1(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32853(MLS000579570 | 2-{[(2,4-dimethylphenyl)sulfonyl]ox...)
Affinity DataEC50:  3.89E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetEndothelial PAS domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32853(MLS000579570 | 2-{[(2,4-dimethylphenyl)sulfonyl]ox...)
Affinity DataIC50: 5.62E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay