BDBM3279 4-(Benzylamino)quinazoline deriv. 30::4-N-benzylquinazoline-4,6-diamine::CHEMBL332096

SMILES Nc1ccc2ncnc(NCc3ccccc3)c2c1

InChI Key InChIKey=KLOMJHRLJJRYDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3279   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3279(CHEMBL332096 | 4-N-benzylquinazoline-4,6-diamine |...)
Affinity DataIC50: 1.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3279(CHEMBL332096 | 4-N-benzylquinazoline-4,6-diamine |...)
Affinity DataIC50: 508nMAssay Description:In vitro inhibition of Epidermal growth factor receptor tyrosine kinase isolated from A431 (human carcinoma).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed