BDBM327899 N5-(1-(4-cyanobenzyl)- 1H-pyrazol-3-yl)-N2-(1- (4- cyanobenzyl)piperidin-4- yl)pyridine-2,5- dicarboxamide::US10377742, Compound 38::US9663496, Compound 38

SMILES O=C(NC1CCN(Cc2ccc(cc2)C#N)CC1)c1ccc(cn1)C(=O)Nc1ccn(Cc2ccc(cc2)C#N)n1

InChI Key InChIKey=OWORLXKPKKUEKB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327899   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327899(N5-(1-(4-cyanobenzyl)- 1H-pyrazol-3-yl)-N2-(1- (4-...)
Affinity DataEC50:  750nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327899(N5-(1-(4-cyanobenzyl)- 1H-pyrazol-3-yl)-N2-(1- (4-...)
Affinity DataEC50:  750nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent